Bird Flu - Information on Bird Flu
by Peter Hutch
Bird flu has led to the deaths of hundreds of millions of wild and domestic birds and to a small number of human deaths. Right now, however, bird flu remains difficult for humans to contract. Most people who have developed symptoms have had close contact with sick birds, though in a few cases, bird flu has passed from one person to another.
Flu viruses occur naturally in birds and have been recognized for more than 100 years. They are popularly known as bird flu, avian flu, bird influenza or avian influenza, and there are more than a dozen sub-types. They are often carried by wild birds, though it is usually domesticated birds that become sick. Generally, the viruses do not affect humans, or cause mild illness at worst.
Diarrhea and Abdominal Pain: Diarrhea and abdominal pain has been a symptom in some patients, but not all of them. Watery diarrhea may be a symptom in bird flu cases, but is not a common symptom in regular flu. Diarrhea comes before respiratory symptoms. Two young patients had encephalitis and diarrhea without any respiratory symptoms. The name H5N1 refers to the type of proteins found in the protein coat of the influenza virus - haemagglutinin 5(H5) and neuraminidase 1 (N1). There are dozens of different proteins that can be present, so that flu viruses called H1N1, H1N2, and H3N2 etc are also known. Officials of the Kano state avian flu control committee detected the presence of Avian flu among 16,000 chickens on a farm a few days ago, a month after the area was declared free of the virus.
Avian influenza cannot be diagnosed by symptoms alone, so a laboratory test is required. Avian influenza is usually diagnosed by collecting a swab from the nose or throat during the first few days of illness. This swab is then sent to a laboratory, where they will either look for avian influenza virus using a molecular test, or they will try to grow the virus. Growing avian influenza viruses should only be done in laboratories with high levels of protection. If it is late in the illness, it may be difficult to find an avian influenza virus directly using these methods.
The virus has been identified in 12 states, including the largest city, Lagos, as well as around the federal capital, Abuja, since it was first confirmed in Nigeria four months ago.
Avian influenza infection in domestic poultry causes two main forms of disease that are distinguished by low and high extremes of virulence. The "low pathogenic" form may go undetected and usually causes only mild symptoms (such as ruffled feathers and a drop in egg production). However, the highly pathogenic form spreads more rapidly through flocks of poultry. It is the highly pathogenic form of H5N1 that concerns scientists.
Avian influenza (or bird flu) is a highly infectious disease affecting many species of birds, including chickens, duck, turkeys and geese. It can affect commercial, wild and pet birds. There are 15 types of bird flu, but the type that is causing concern at the moment is the deadly strain H5N1.
Avian flu passes from birds to other birds, but there have also been human cases. As of January 2007, the World Health Organization (WHO) had confirmed 270 cases of H5N1 in humans in Azerbaijan, Cambodia, China, Djibouti, Egypt, Indonesia, Iraq, Thailand, Turkey and Vietnam, leading to 164 deaths.
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CUT THE CHAIN OF INFECTIONS !
Spread of avian flu by drinking water:
Proved awareness to ecology and transmission is necessary to understand the spread of avian flu. For this it is insufficient exclusive to test samples from wild birds, poultry and humans for avian flu viruses. Samples from the known abiotic vehicles also have to be analysed. There are plain links between the cold, rainy seasons as well as floods and the spread of avian flu. That is just why abiotic vehicles have to be analysed. The direct biotic transmission from birds, poultry or humans to humans can not depend on the cold, rainy seasons or floods. Water is a very efficient abiotic vehicle for the spread of viruses - in particular of fecal as well as by mouth, nose and eyes excreted viruses.
Infected birds and poultry can everywhere contaminate the drinking water. All humans have very intensive contact to drinking water. Spread of avian flu by drinking water can explain small clusters in households too. Proving viruses in water is difficult because of dilution. If you find no viruses you can not be sure that there are not any. On the other hand in water viruses remain viable for a long time. Water has to be tested for influenza viruses by cell culture and in particular by the more sensitive molecular biology method PCR.
There is a widespread link between avian flu and water, e.g. in Egypt to the Nile delta or Indonesia to residential districts of less prosperous humans with backyard flocks and without central water supply as in Vietnam: http://www.cdc.gov/ncidod/EID/vol12no12/06-0829.htm. See also the WHO web side: http://www.who.int/water_sanitation_health/emerging/h5n1background.pdf.
Transmission of avian flu by direct contact to infected poultry is an unproved assumption from the WHO. There is no evidence that influenza primarily is transmitted by saliva droplets: “Transmission of influenza A in human beings” http://www.thelancet.com/journals/laninf/article/PIIS1473309907700294/abstract?iseop=true.
Avian flu infections may increase in consequence to increase of virus circulation. Human to human and contact transmission of influenza occur - but are overvalued immense. In the course of influenza epidemics in Germany, recognized clusters are rare, accounting for just 9 percent of cases e.g. in the 2005 season. In temperate climates the lethal H5N1 virus will be transferred to humans via cold drinking water, as with the birds in February and March 2006, strong seasonal at the time when drinking water has its temperature minimum.
The performance to eliminate viruses from the drinking water processing plants regularly does not meet the requirements of the WHO and the USA/USEPA. Conventional disinfection procedures are poor, because microorganisms in the water are not in suspension, but embedded in particles. Even ground water used for drinking water is not free from viruses.
In temperate regions influenza epidemics recur with marked seasonality around the end of winter, in the northern as well as in the southern hemisphere. Although seasonality is one of the most familiar features of influenza, it is also one of the least understood. Indoor crowding during cold weather, seasonal fluctuations in host immune responses, and environmental factors, including relative humidity, temperature, and UV radiation have all been suggested to account for this phenomenon, but none of these hypotheses has been tested directly. Influenza causes significant morbidity in tropical regions; however, in contrast to the situation in temperate zones, influenza in the tropics is not strongly associated with a certain season.
There are clear links between the cold, rainy seasons as well as floods and the spread of influenza. There is a widespread link between avian flu and water, e.g. in Egypt to the Nile delta or in Indonesia to residential districts of less prosperous humans with backyard flocks of birds and without a central water supply as in Vietnam. The direct biotic transmission from birds, poultry or humans to humans cannot be dependent on the cold, rainy seasons or floods. Water is a very efficient abiotic vehicle for the spread of viruses - in particular of fecal as well as viruses excreted through the mouth, nose and eyes. Infected humans, mammals, birds and poultry can contaminate drinking water everywhere. All humans have very intensive contact to drinking water.
In the tropics, flood-related influenza is typical after extreme weather and floods. The virulence of influenza viruses depends on temperature and time. Especially in cases of local water supplies with “young” and fresh influenza-contaminated water from low local wells, cisterns, tanks, rain barrels, ponds, rivers or rice paddies, this pathway can explain small clusters in households, too. At 24°C, for example, in the tropics the virulence of influenza viruses in water exists for 2 days. In temperate climates with “older” water from central water supplies, the temperature of the water is decisive for the virulence of viruses. At 7°C the virulence of influenza viruses in water extends to 14 days.
http://www.un.org/apps/news/story.asp?NewsID=26096&Cr=&Cr1
Ducks and rice (paddies = flooded by water) are major factors in outbreaks of avian flu, claims a UN agency: Ducks and rice fields may be a critical factor in spreading H5N1. Ducks, rice (fields, paddies = flooded by water; farmers at work drink the water from rice paddies) and people – not chickens – have emerged as the most significant factors in the spread of avian influenza in Thailand and Vietnam, according to a study carried out by a group of experts from the United Nations Food and Agriculture Organization (FAO) and associated research centres.
The study “Mapping H5N1 highly pathogenic avian influenza risk in Southeast Asia: ducks, rice and people” also concludes that these factors are probably behind persistent outbreaks in other countries such as Cambodia and Laos.
This study examined a series of waves of H5N1, a highly pathogenic avian influenza, in Thailand and Vietnam between early 2004 and late 2005. Through the use of satellite mapping, researchers looked at several different factors, including the numbers of ducks, geese and chickens, human population size, rice cultivation and geography, and found a strong link between duck grazing patterns and rice cropping intensity.
In Thailand, for example, the proportion of young ducks in flocks was found to peak in September-October; these rapidly growing young ducks can therefore benefit from the peak of the rice harvest in November-December, at the beginning of the cold: Thailand, Vietnam, Cambodia, Laos – as opposed to Indonesia – are located in the northern hemisphere.
These peaks in the congregation of ducks indicate periods in which there is an increase in the chances for virus release and exposure, and rice paddies often become a temporary habitat for wild bird species. In addition, with virus persistence becoming increasingly confined to areas with intensive rice-duck agriculture in eastern and south-eastern Asia, the evolution of the H5N1 virus may become easier to predict.
The FAO estimates that approximately 90 percent of the world’s more than 1 billion domestic ducks are in Asia, with about 75 percent of those in China and Vietnam. Thailand has about 11 million ducks.
Dipl.-Ing. Wilfried Soddemann - Epidemiologist - Free Science Journalist soddemann-aachen@t-online.de http://www.dugi-ev.de/information.html
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